From the New York Times bestselling author ofChasing the Scream: The First and Last Days of the War on Drugs, a startling challenge to our thinking about depression and anxiety.Award-winning journalist Johann Hari suffered from depression since he was a child and started taking antidepressants when he was a teenager. He was toldlike his entire generationthat his problem was caused by a chemical imbalance in his brain. As an adult, trained in the social sciences, he began to investigate this questionand he learned that almost everything we have been told about depression and anxiety is wrong.Across the world, Hari discovered social scientists who were uncovering the real causesand they are mostly not in our brains, but in the way we live today. Haris journey took him from the people living in the tunnels beneath Las Vegas, to an Amish community in Indiana, to an uprising in Berlinall showing in vivid and dramatic detail these new insights. They lead to solutions radically different from the ones we have been offered up until now.Just asChasing the Screamtransformed the global debate about addiction, with over twenty million views for his TED talk and the animation based on it,Lost Connectionswill lead us to a very different debate about depression and anxietyone that shows how, together, we can end this epidemic.